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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 22.12
Human Site: S472 Identified Species: 34.76
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S472 C S S P S T I S P P K G C P R
Chimpanzee Pan troglodytes XP_001159776 886 99121 S469 C S S P S T I S P P K G C P R
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S585 C S S P S T I S P P K G C P R
Dog Lupus familis XP_548434 951 104664 S534 C S S P S T I S P P K A C P Q
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 P461 L L P P C S S P N T A S P P K
Rat Rattus norvegicus O08874 985 112050 S536 V N H S G T F S P Q T P V P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 S570 L P P C G S P S S T L S P P S
Chicken Gallus gallus XP_422357 1013 114806 S608 P P A P P R A S S L G E I C E
Frog Xenopus laevis Q7ZX15 486 56292 Q140 S D V S S A E Q M D V A M S K
Zebra Danio Brachydanio rerio XP_697542 940 106140 S524 N S T I T A L S P P L P G S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 G288 V T G S G G V G A T G E T R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 Y348 S N S E N S G Y L Q Q I S E D
Sea Urchin Strong. purpuratus XP_787090 799 90414 S361 S L T P S G T S P P T A I R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 P591 R A N A P L P P Q P R K H D K
Red Bread Mold Neurospora crassa P87253 1142 127954 G718 Y S A Q Q Q Q G Y G S P Q Q R
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 100 86.6 N.A. 13.3 26.6 N.A. 13.3 13.3 6.6 26.6 N.A. 0 N.A. 6.6 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 26.6 33.3 N.A. 20 20 13.3 46.6 N.A. 13.3 N.A. 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 14 7 0 14 7 0 7 0 7 20 0 0 7 % A
% Cys: 27 0 0 7 7 0 0 0 0 0 0 0 27 7 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 7 0 0 0 7 7 % D
% Glu: 0 0 0 7 0 0 7 0 0 0 0 14 0 7 14 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 20 14 7 14 0 7 14 20 7 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 7 0 0 27 0 0 0 0 7 14 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 27 7 0 0 20 % K
% Leu: 14 14 0 0 0 7 7 0 7 7 14 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % M
% Asn: 7 14 7 0 7 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 7 14 14 47 14 0 14 14 47 47 0 20 14 47 14 % P
% Gln: 0 0 0 7 7 7 7 7 7 14 7 0 7 7 7 % Q
% Arg: 7 0 0 0 0 7 0 0 0 0 7 0 0 14 27 % R
% Ser: 20 40 34 20 40 20 7 60 14 0 7 14 7 14 7 % S
% Thr: 0 7 14 0 7 34 7 0 0 20 14 0 7 0 0 % T
% Val: 14 0 7 0 0 0 7 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _